Kiyohiko Sugano : rechercher sur Z-Library

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1

Oral Absorption of Poorly Water-Soluble Drugs: Computer Simulation of Fraction Absorbed in Humans from a Miniscale Dissolution Test

Ryusuke Takano, Kiyohiko Sugano, Atsuko Higashida, Yoshiki Hayashi, Minoru Machida, Yoshinori Aso, Shinji Yamashita

Journal:

Pharmaceutical Research

Année:

2006

Langue:

english

Fichier:

PDF, 421 KB

english, 2006

2

Computational Oral Absorption Simulation for Low-Solubility Compounds

Kiyohiko Sugano

Journal:

Chemistry & Biodiversity

Année:

2009

Langue:

english

Fichier:

PDF, 509 KB

english, 2009

3

A simulation of oral absorption using classical nucleation theory

Kiyohiko Sugano

Journal:

International Journal of Pharmaceutics

Année:

2009

Langue:

english

Fichier:

PDF, 258 KB

english, 2009

4

Application of the BCS biowaiver approach to assessing bioequivalence of orally disintegrating tablets with immediate release formulations

Ono, Asami, Sugano, Kiyohiko

Journal:

European Journal of Pharmaceutical Sciences

Année:

2014

Langue:

english

Fichier:

PDF, 529 KB

english, 2014

5

Rate- and Extent-Limiting Factors of Oral Drug Absorption: Theory and Applications

Sugano, Kiyohiko, Terada, Katsuhide

Journal:

Journal of Pharmaceutical Sciences

Année:

2015

Langue:

english

Fichier:

PDF, 505 KB

english, 2015

6

Solubility and Dissolution Profile Assessment in Drug Discovery

Sugano, Kiyohiko, Okazaki, Arimichi, Sugimoto, Shohei, Tavornvipas, Sumitra, Omura, Atsushi, Mano, Takashi

Journal:

Drug Metabolism and Pharmacokinetics

Année:

2007

Langue:

english

Fichier:

PDF, 1.41 MB

english, 2007

7

Theoretical dissolution model of poly-disperse drug particles in biorelevant media

Arimichi Okazaki, Takashi Mano, Kiyohiko Sugano

Journal:

Journal of Pharmaceutical Sciences

Année:

2008

Langue:

english

Fichier:

PDF, 153 KB

english, 2008

8

Prediction of oral drug absorption in humans by theoretical passive absorption model

Kouki Obata, Kiyohiko Sugano, Ryoichi Saitoh, Atsuko Higashida, Yoshiaki Nabuchi, Minoru Machida, Yosinori Aso

Journal:

International Journal of Pharmaceutics

Année:

2005

Langue:

english

Fichier:

PDF, 237 KB

english, 2005

9

Estimation of effective intestinal membrane permeability considering bile micelle solubilisation

Kiyohiko Sugano

Journal:

International Journal of Pharmaceutics

Année:

2009

Langue:

english

Fichier:

PDF, 530 KB

english, 2009

10

Fraction of a dose absorbed estimation for structurally diverse low solubility compounds

Kiyohiko Sugano

Journal:

International Journal of Pharmaceutics

Année:

2011

Langue:

english

Fichier:

PDF, 391 KB

english, 2011

11

Quantitative structure–intestinal permeability relationship of benzamidine analogue thrombin inhibitor

Kiyohiko Sugano, Shoshin Yoshida, Mikio Takaku, Masayuki Haramura, Ryoichi Saitoh, Yoshiaki Nabuchi, Hidetoshi Ushio

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2000

Langue:

english

Fichier:

PDF, 136 KB

english, 2000

12

Coexistence of passive and carrier-mediated processes in drug transport

Sugano, Kiyohiko, Kansy, Manfred, Artursson, Per, Avdeef, Alex, Bendels, Stefanie, Di, Li, Ecker, Gerhard F., Faller, Bernard, Fischer, Holger, Gerebtzoff, Grégori

Journal:

Nature Reviews Drug Discovery

Année:

2010

Langue:

english

Fichier:

PDF, 599 KB

english, 2010

13

Application of Dissolution/Permeation System for Evaluation of Formulation Effect on Oral Absorption of Poorly Water-Soluble Drugs in Drug Development

Makoto Kataoka, Kiyohiko Sugano, Claudia da Costa Mathews, Jing Wen Wong, Kelly Lane Jones, Yoshie Masaoka, Shinji Sakuma, Shinji Yamashita

Journal:

Pharmaceutical Research

Année:

2012

Langue:

english

Fichier:

PDF, 398 KB

english, 2012

14

Prediction of food effect by bile micelles on oral drug absorption considering free fraction in intestinal fluid

Kiyohiko Sugano, Makoto Kataoka, Claudia da Costa Mathews, Shinji Yamashita

Journal:

European Journal of Pharmaceutical Sciences

Année:

2010

Langue:

english

Fichier:

PDF, 331 KB

english, 2010

15

Introduction to computational oral absorption simulation

Sugano, Kiyohiko

Journal:

Expert Opinion on Drug Metabolism & Toxicology

Année:

2009

Langue:

english

Fichier:

PDF, 3.24 MB

english, 2009

16

Biopharmaceutics Modeling and Simulations (Theory, Practice, Methods, and Applications) || Intestinal Transporters

Sugano, Kiyohiko

Année:

2012

Langue:

english

Fichier:

PDF, 187 KB

english, 2012

17

Biopharmaceutics Modeling and Simulations (Theory, Practice, Methods, and Applications) || Epistemology of Biopharmaceutical Modeling and Good Simulation Practice

Sugano, Kiyohiko

Année:

2012

Langue:

english

Fichier:

PDF, 64 KB

english, 2012

18

Biopharmaceutics Modeling and Simulations (Theory, Practice, Methods, and Applications) || Enabling Formulations

Sugano, Kiyohiko

Année:

2012

Langue:

english

Fichier:

PDF, 337 KB

english, 2012

19

Biopharmaceutics Modeling and Simulations (Theory, Practice, Methods, and Applications) || Dose and Particle Size Dependency

Sugano, Kiyohiko

Année:

2012

Langue:

english

Fichier:

PDF, 103 KB

english, 2012

20

Biopharmaceutics Modeling and Simulations (Theory, Practice, Methods, and Applications) || Biopharmaceutical Modeling for Miscellaneous Cases

Sugano, Kiyohiko

Année:

2012

Langue:

english

Fichier:

PDF, 338 KB

english, 2012

21

Biopharmaceutics Modeling and Simulations (Theory, Practice, Methods, and Applications) || Food Effect

Sugano, Kiyohiko

Année:

2012

Langue:

english

Fichier:

PDF, 560 KB

english, 2012

22

Biopharmaceutics Modeling and Simulations (Theory, Practice, Methods, and Applications) || Bioequivalence and Biopharmaceutical Classification System

Sugano, Kiyohiko

Année:

2012

Langue:

english

Fichier:

PDF, 210 KB

english, 2012

23

Biopharmaceutics Modeling and Simulations (Theory, Practice, Methods, and Applications) || Strategy in Drug Discovery and Development

Sugano, Kiyohiko

Année:

2012

Langue:

english

Fichier:

PDF, 110 KB

english, 2012

24

Theoretical comparison of hydrodynamic diffusion layer models used for dissolution simulation in drug discovery and development

Sugano, Kiyohiko

Journal:

International Journal of Pharmaceutics

Année:

2008

Langue:

english

Fichier:

PDF, 288 KB

english, 2008

25

Prediction Accuracy of Mechanism-Based Oral Absorption Model for Dogs

Akiyama, Yoshiyuki, Kimoto, Takahiro, Mukumoto, Hanae, Miyake, Shuji, Ito, Soichiro, Taniguchi, Toshio, Nomura, Yukihiro, Matsumura, Naoya, Fujita, Takuya, Sugano, Kiyohiko

Journal:

Journal of Pharmaceutical Sciences

Année:

2019

Langue:

english

Fichier:

PDF, 553 KB

english, 2019

26

The Critical Role of Passive Permeability in Designing Successful Drugs

Di, Li, Artursson, Per, Avdeef, Alex, Benet, Leslie, Houston, Brian, Kansy, Manfred, Kerns, Edward, LennernÃ¤s, Hans, Smith, Dennis, Sugano, Kiyohiko

Journal:

Année:

2020

Fichier:

PDF, 1.27 MB

2020

27

ChemInform Abstract: Computational Oral Absorption Simulation for Low-Solubility Compounds.

Kiyohiko Sugano

Journal:

Année:

2010

Fichier:

PDF, 15 KB

2010

28

High throughput solubility measurement with automated polarized light microscopy analysis

Kiyohiko Sugano, Teruhisa Kato, Kentaro Suzuki, Kako Keiko, Tetsujo Sujaku, Takashi Mano

Journal:

Journal of Pharmaceutical Sciences

Année:

2006

Langue:

english

Fichier:

PDF, 235 KB

english, 2006

29

PAMPA—critical factors for better predictions of absorption

Alex Avdeef, Stefanie Bendels, Li Di, Bernard Faller, Manfred Kansy, Kiyohiko Sugano, Yukinori Yamauchi

Journal:

Journal of Pharmaceutical Sciences

Année:

2007

Langue:

english

Fichier:

PDF, 1.10 MB

english, 2007

30

Permeation characteristics of a hydrophilic basic compound across a bio-mimetic artificial membrane

Kiyohiko Sugano, Yoshiaki Nabuchi, Minoru Machida, Yoshinori Asoh

Journal:

International Journal of Pharmaceutics

Année:

2004

Langue:

english

Fichier:

PDF, 124 KB

english, 2004

31

Solid form selection of zwitterionic 5-HT4 receptor agonist

Takashi Kojima, Kiyohiko Sugano, Satomi Onoue, Noriaki Murase, Morimichi Sato, Yohei Kawabata, Takashi Mano

Journal:

International Journal of Pharmaceutics

Année:

2008

Langue:

english

Fichier:

PDF, 812 KB

english, 2008

32

Theoretical investigation of passive intestinal membrane permeability using Monte Carlo method to generate drug-like molecule population

Kiyohiko Sugano

Journal:

International Journal of Pharmaceutics

Année:

2009

Langue:

english

Fichier:

PDF, 749 KB

english, 2009

33

Possible reduction of effective thickness of intestinal unstirred water layer by particle drifting effect

Kiyohiko Sugano

Journal:

International Journal of Pharmaceutics

Année:

2010

Langue:

english

Fichier:

PDF, 680 KB

english, 2010

34

Computational oral absorption simulation of free base drugs

Kiyohiko Sugano

Journal:

International Journal of Pharmaceutics

Année:

2010

Langue:

english

Fichier:

PDF, 419 KB

english, 2010

35

Optimized conditions of bio-mimetic artificial membrane permeation assay

Kiyohiko Sugano, Hirokazu Hamada, Minoru Machida, Hidetoshi Ushio, Kimitoshi Saitoh, Katsuhide Terada

Journal:

International Journal of Pharmaceutics

Année:

2001

Langue:

english

Fichier:

PDF, 174 KB

english, 2001

36

Prediction of passive intestinal absorption using bio-mimetic artificial membrane permeation assay and the paracellular pathway model

Kiyohiko Sugano, Noriyuki Takata, Minoru Machida, Kimitoshi Saitoh, Katsuhide Terada

Journal:

International Journal of Pharmaceutics

Année:

2002

Langue:

english

Fichier:

PDF, 144 KB

english, 2002

37

Prediction of human intestinal permeability using artificial membrane permeability

Kiyohiko Sugano, Yoshiaki Nabuchi, Minoru Machida, Yoshinori Aso

Journal:

International Journal of Pharmaceutics

Année:

2003

Langue:

english

Fichier:

PDF, 106 KB

english, 2003

38

Corrigendum to “Quantitative structure–Intestinal permeability relationship of benzamidine analogue thrombin inhibitor”: [Bioorg. Med. Chem. Lett. 10 (2000) 1939]

Kiyohiko Sugano, Shoshin Yoshida, Mikio Takaku, Masayuki Haramura, Ryoichi Saitoh, Yoshiaki Nabuchi, Hidetoshi Ushio

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2001

Langue:

english

Fichier:

PDF, 63 KB

english, 2001

39

Gene expression profiles and microsatellite instability in uterine corpus endometrioid adenocarcinoma

Yasuko Koyamatsu, Masaru Sakamoto, Kiyohiko Miyake, Tetsuya Muroya, Kokichi Sugano, Yoshifumi Nakao, Masatoshi Yokoyama, Tsuyoshi Iwasaka

Journal:

Journal of Obstetrics and Gynaecology Research

Année:

2010

Langue:

english

Fichier:

PDF, 725 KB

english, 2010

40

Correction of Permeability with Pore Radius of Tight Junctions in Caco-2 Monolayers Improves the Prediction of the Dose Fraction of Hydrophilic Drugs Absorbed by Humans

Ryoichi Saitoh, Kiyohiko Sugano, Noriyuki Takata, Tatsuhiko Tachibana, Atsuko Higashida, Yoshiaki Nabuchi, Yoshinori Aso

Journal:

Pharmaceutical Research

Année:

2004

Langue:

english

Fichier:

PDF, 111 KB

english, 2004

41

Estimation of Michaelis–Menten constant of efflux transporter considering asymmetric permeability

Kiyohiko Sugano, Yoshiyuki Shirasaka, Shinji Yamashita

Journal:

International Journal of Pharmaceutics

Année:

2011

Langue:

english

Fichier:

PDF, 475 KB

english, 2011

42

Evidence-based approach to assess passive diffusion and carrier-mediated drug transport

Li Di, Per Artursson, Alex Avdeef, Gerhard F. Ecker, Bernard Faller, Holger Fischer, J. Brian Houston, Manfred Kansy, Edward H. Kerns, Stefanie D. Krämer, Hans Lennernäs, Kiyohiko Sugano

Journal:

Drug Discovery Today

Année:

2012

Langue:

english

Fichier:

PDF, 518 KB

english, 2012

43

Biopharmaceutics Modeling and Simulations (Theory, Practice, Methods, and Applications) || Theoretical Framework II: Dissolution

Sugano, Kiyohiko

Année:

2012

Langue:

english

Fichier:

PDF, 433 KB

english, 2012

44

Biopharmaceutics Modeling and Simulations (Theory, Practice, Methods, and Applications) || Theoretical Framework I: Solubility

Sugano, Kiyohiko

Année:

2012

Langue:

english

Fichier:

PDF, 460 KB

english, 2012

45

Biopharmaceutics Modeling and Simulations (Theory, Practice, Methods, and Applications) || Introduction

Sugano, Kiyohiko

Année:

2012

Langue:

english

Fichier:

PDF, 262 KB

english, 2012

46

Biopharmaceutics Modeling and Simulations (Theory, Practice, Methods, and Applications) || Physiology of Gastrointestinal Tract and Other Administration Sites in Humans and Animals

Sugano, Kiyohiko

Année:

2012

Langue:

english

Fichier:

PDF, 1015 KB

english, 2012

47

Biopharmaceutics Modeling and Simulations (Theory, Practice, Methods, and Applications) || Theoretical Framework IV: Gastrointestinal Transit Models and Integration

Sugano, Kiyohiko

Année:

2012

Langue:

english

Fichier:

PDF, 514 KB

english, 2012

48

Biopharmaceutics Modeling and Simulations (Theory, Practice, Methods, and Applications) || Theoretical Framework III: Biological Membrane Permeation

Sugano, Kiyohiko

Année:

2012

Langue:

english

Fichier:

PDF, 1001 KB

english, 2012

49

Biopharmaceutics Modeling and Simulations (Theory, Practice, Methods, and Applications) || Validation of Mechanistic Models

Sugano, Kiyohiko

Année:

2012

Langue:

english

Fichier:

PDF, 629 KB

english, 2012

50

Biopharmaceutics Modeling and Simulations (Theory, Practice, Methods, and Applications) || Drug Parameters

Sugano, Kiyohiko

Année:

2012

Langue:

english

Fichier:

PDF, 729 KB

english, 2012